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Difference – Unfractionated (Standard) Heparin and LMWH (Low Molecular Weight Heparin)

Unfractionated heparin is largely replaced by low molecular weight heparin in the management of venous thromboembolism treatment and management and acute coronary syndrome. LMWH (Low molecular weight heparin) is also preferably used for venous thrombosis prophylaxis. Difference between unfractionated heparin and low molecular weight heparin. Difference between unfractionated heparin and low molecular weight heparin is explained [...]

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Lithium toxicity – Signs and symptoms, Causes and Management.

Lithium is a metal, but in medicine, it is used to treat bipolar disorder and refractory depression. Refractory depression means depression that failed other recommended medical management. Lithium is excreted through the kidneys, therefore, your patient must have a normal renal function if you want to initiate lithium therapy. It has a very narrow therapeutic range,

By | Drug Information, Medical Guidelines, Poisoning and toxicology | Like |

Sublingual Captopril (Capoten) is linked with major stroke and death. no longer recommended.

Previously sublingual captopril was given to lower blood pressure in the emergency room. But several cases of large cerebral stroke are reported and it is no longer used worldwide. But in developing countries and peripheral rural areas, it is still used by those physicians who don’t have the means to get the latest information, either electronically,

By | Dr. Adil Ramzan, Dr. Rauf Niazi, Drug Information, General Health Info, Medical Research | Like |

Letrozole vs clomiphene for pregnancy in polycystic ovarian syndrome

Letrozole which is an aromatase inhibitor, which blocks the conversion of testosterone to estrogen and thus blocks the negative feedback effect of estrogen on FSH. Therefore, the level of FSH increases and the chance of follicle maturity increases.

Clomiphene also works by increasing the level of FSH and LH. but clomphene acts directly on hypothalamus.

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Antithyroid drug to treat Hyperthyroidism in Pregnancy – Precautions

Hyperthyroidism in pregnancy should be managed cautiously, but management is necessary. Anti-thyroid drugs such as Methimazole and Carbimazole are teratogenic and must be avoided in pregnancy especially in the 1st trimester. So in pregnancy, the drug of choice for hyperthyroidism is Propylthiouracil (PTU) But Propylthiouracil is potentially hepatotoxic. So closely monitor the liver function tests and [...]

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Oritavancin vs Vancomycin for treatment of gram positive infections

OritavancinVancomycinOritavancin Vs Vancomycin Reference / CreditsOritavancin Oritavancin has a chemical structure similar to that of Vancomycin. Oritavancin is a lipoglycopeptide and is effective against gram-positive bacteria including Methicillin-Resistant Staphylococcus Aureus (MRSA). It is available in the market with the name of Orbactiv®. Vancomycin Vancomycin is also a lipoglycopeptide antibiotic and is effective against gram-positive organisms including [...]

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