Antithyroid drug to treat Hyperthyroidism in Pregnancy – Precautions

Hyperthyroidism in pregnancy should be managed cautiously, but management is necessary. Anti-thyroid drugs such as Methimazole and Carbimazole are teratogenic and must be avoided in pregnancy especially in the 1st trimester. So in pregnancy, the drug of choice for hyperthyroidism is Propylthiouracil (PTU) But Propylthiouracil is potentially hepatotoxic. So closely monitor the liver function tests and [...]

Corrected Reticulocyte Count for RBCs Formula or Absolute reticulocyte count

In case of anemia, corrected reticulocyte count for Red blood cells or absolute reticulocyte count must be used instead of simple reticulocyte percentage because reticulocyte percentage is simply the ratio of reticulocytes to red blood cells, which may give a falsely high reading of reticulocyte percentage when the number of RBCs is low. Let's have an [...]

Cushing’s Syndrome – Diagnostic and Management Guidelines

Cushing's Syndrome vs DiseaseEpidemiologyCauses Clinical FeaturesDiagnosisTreatmentAuthor - ReferencesCushing's Syndrome vs Disease Cushing’s syndrome Cushing’s syndrome is a condition that results from long-term exposure to corticosteroids due to any etiology.   Cushing’s disease If ACTH excess is the cause of hypercortisolism due to a pituitary gland tumor then, in this case, it is called Cushing’s disease instead [...]

How Rapidly Should Hyponatremia Be Corrected? Hyponatremia Correction Rate

Hyponatremia ReferenceHyponatremia Hyponatremia is defined as serum sodium concentration of less than 135mEq/L. Mild Hyponatremia: Serum Sodium: 130-134 mEq/L Moderate Hyponatremia: Serum Sodium: 125-129 mEq/L Severe Hyponatremia: Serum Sodium: < 125 mEq/L Correction Rate If a patient has mild hyponatremia, then only water restriction may improve the serum sodium concentration. If the duration of hyponatremia is less [...]
treatment of chickenpox in pregnancy

Treatment of Chickenpox During Pregnancy. Post Exposure & Post Diagnosis

Chicken Pox in PregnancyExposure to ChickenpoxTreatment in PregnancyReferences / CreditsChicken Pox in Pregnancy Chickenpox in pregnancy is a serious condition which must be treated, Pregnant Patients present to outpatient or emergency department with chickenpox lesions, so the health care practitioner must know how to deal with such condition, as if untreated, it may cause fetal [...]

Oritavancin vs Vancomycin for treatment of gram positive infections

OritavancinVancomycinOritavancin Vs Vancomycin Reference / CreditsOritavancin Oritavancin has a chemical structure similar to that of Vancomycin. Oritavancin is a lipoglycopeptide and is effective against gram-positive bacteria including Methicillin-Resistant Staphylococcus Aureus (MRSA). It is available in the market with the name of Orbactiv®. Vancomycin Vancomycin is also a lipoglycopeptide antibiotic and is effective against gram-positive organisms including [...]

Guidelines: Management Approach to Sepsis / Septic Shock – Summary

Background Stages of Sepsis Diagnosis of Sepsis Management of Sepsis References / Credits In order to manage a patient suferring from sepsis, you must first know the stage of sepsis the patient is suffering from because the management is different for each stage. Sepsis is defined as systemic inflammatory response syndrome as a result of [...]
Dr. Adil Ramzan, Adil Ramzan

Aplastic Anemia ppt Presentation, Lecture, Dr. Adil Ramzan

Aplastic anemia is a syndrome of pancytopenia and hypocellular bone marrow. The differential point of Aplastic anemia is that there must not be any abnormal hematopoietic cell in the peripheral film or bone marrow.

Dr. Adil Ramzan, MBBS, MD Internal Medicine resident talks about aplastic anemia at Pakistan Institute of Medical Science, Shaheed Zulfiqar Ali Bhutto Medical University Islamabad in June 2016.

Dr. Adil Ramzan

When Metformin, if given, increases mortality? Dr. Adil Ramzan

Studies have shown Metformin has a number of benefits, some say it is a miraculous drug. Metformin has shown following properties;

  1. Its antiging
  2. It reduces the risk of cancer
  3. Decreases the risk of stroke, cardiovascular diseases,
  4. Decreases progression of atherosclerosis
  5. Reduces the risk of developing open angle glaucoma
  6. Helps to induce ovulation in polycystic cystic ovarian syndrome.